Hi,
I'm just curious to know whether or not you have any plans to start compiling the packages with -O3? If I recall correctly then GCC have a generic O3 option, which should work across almost all CPUs, except ancient ones ;)
Replacing Arch's repos with those from ALHP (https://git.harting.dev/ALHP/ALHP.GO) did provide a noticable performance lift for those packages from that repo - since that was limited to userspace tools, I wonder the potential for Artix' packages compiled with -O3 (and perhaps LTO) :)
Gentoo (https://wiki.gentoo.org/wiki/Handbook:AMD64/Installation/Stage#CFLAGS_and_CXXFLAGS) doesn't recommend enabling it system-wide:
Also (https://wiki.gentoo.org/wiki/GCC_optimization):