I don't user virtmanager, but qemu direct:
qemu-system-x86_64 -enable-kvm -cpu host -smp cores=4 -m 4G -vga none -device virtio-vga-gl -display sdl,gl=on -audio sdl,model=hda -drive file=[qcow2-Image],if=virtio,aio=io_uring,discard=unmap
Btw: With Runit I had the most less Problems: In real and in VMs.